TiMESH – Animal Studies

Porcine Models
12 weeks postoperative


Scheidbach H, Tannapfel A, Schmidt U, Lippert H, Kӧckerling F (2004) Influence of titanium coating on the biocompatibility of a heavyweight polypropylene mesh. Eur Surg Res 36:313–317

Schug-Pass C, Lippert H, Kӧckerling F (2009) Fixation of mesh to the peritoneum using a fibrin glue: investigations with a biomechanical model and an experimental laparoscopic porcine model. Surg Endosc 23:2809–2815

Junge K, Rosch R, Klinge U, Saklak M, Klosterhalfen B, Peiper C, Schumpelick V (2005) Titanium coating of a polypropylene mesh for hernia repair: effect on biocompatibility. Hernia 9:115–119

Pereira-Lucena CG, Artigiani-Neto A, Lopes-Filho GJ, Frazao CVG, Goldenberg A, Matos D, Linhares MM (2010) Experimental study comparing meshes made of polypropylene, polypropylene + polyglactin and polypropylene + titanium: inflammatory cytokines, histological changes and morphometric analysis of collagen. Hernia 14:299–304

Burger JWA, Halm JA, Wijsmuller AR, ten Raa S, Jeekel J (2006) Evaluation of new prosthetic meshes for ventral hernia repair. Surg Endosc 20:1320–1325

Chatzimavroudis G, Koutelidakis I, Papaziogas B, Tsaganos T, Koutoukas P, Giamarellos-Bourboulis E, Atmatzidis S,Atmatzidis K (2008) The effect of the type of intraperitoneally implanted prosthetic mesh on the systemic inflammatory response. Hernia 12:277–283

Schreinemacher MHF, Emans PJ, Gijbels MJJ, Greve JWM, Beets GL, Bouvy ND (2009) Degradation of mesh coatings and intraperitoneal adhesion formation in an experimental model. Br J Surg 96:305–313

Ott R, Hartwig T, Tannapfel A, Blatz R, Rodloff AC, Madaj-Sterba P, Mo¨bius C, Kӧckerling F (2007) Biocompatibility of bacterial contaminated prosthetic meshes and porcine dermal collagen used to repair abdominal wall defects. Langenbecks Arch Surg 392:473–478

Fortelny RH, Pettert-Puchner AH, Walder N, Mittermayr R, Ӧhlinger W, Heinze A, Redl H (2007) Cyanoacrylate tissue sealant impairs tissue integration of macroporous mesh in experimental hernia repair. Surg Endosc 21:1781–1785

Scheidbach H, Tamme C, Tannapfel A, Lippert H, Kӧckerling F (2004) In vivo studies comparing the biocompatibility of various polypropylene meshes and their handling properties during endoscopic total extraperitoneal (TEP) patch plasty. Surg Endosc 18:211–220

Schug-Pass C, Tamme C, Tannapfel A, Kӧckerling F (2006) A lightweight polypropylene mesh (TiMesh) for laparoscopic intraperitoneal repair of abdominal wall hernias. Surg Endosc 20:402–409

Schug-Pass C, Sommerer F, Tannapfel A, Lippert H, Kӧckerlin F (2008) Does the additional application of a polylactide film (SurgiWrap) to a lightweight mesh (TiMesh) reduce adhesions after laparoscopic intraperitoneal implantation procedures? Experimental results obtained with the laparoscopic porcine model. Surg Endosc 22:2433–2439